Comments on: Nerve cell talk – sertraline (Zoloft) http://drajit.wordpress.com/2008/12/05/nerve-cell-talk-anti-depressant-sertraline-zoloft/ Just another WordPress.com weblog Fri, 14 Aug 2009 23:02:29 +0000 http://wordpress.com/ hourly 1 By: Paul http://drajit.wordpress.com/2008/12/05/nerve-cell-talk-anti-depressant-sertraline-zoloft/#comment-60 Paul Sat, 13 Dec 2008 22:09:14 +0000 http://drajit.wordpress.com/?p=72#comment-60 Thanks for your clear presentation of this complex material, nice job! Thanks for your clear presentation of this complex material, nice job!

]]> By: Doc http://drajit.wordpress.com/2008/12/05/nerve-cell-talk-anti-depressant-sertraline-zoloft/#comment-59 Doc Fri, 12 Dec 2008 16:14:50 +0000 http://drajit.wordpress.com/?p=72#comment-59 I would only offer a couple of points: 1. The increased irritability in young adults is often due to undiagnosed bipolar disorder; and SSRI's (and most other antidepressants) can trigger a manic or mixed state episode. 2. Zoloft has a bit of secondary activity on Dopamine, which may be somewhat pro-cognitive and pro-motivation. 3. Most studies have shown that the most effective treatment of depression is a combination of therapy (Cognitive-Behavioral has been most studied) and medications. Thanks for the nice article, I'll be linking to it. I would only offer a couple of points:
1. The increased irritability in young adults is often due to undiagnosed bipolar disorder; and SSRI’s (and most other antidepressants) can trigger a manic or mixed state episode.
2. Zoloft has a bit of secondary activity on Dopamine, which may be somewhat pro-cognitive and pro-motivation.
3. Most studies have shown that the most effective treatment of depression is a combination of therapy (Cognitive-Behavioral has been most studied) and medications.

Thanks for the nice article, I’ll be linking to it.

]]>